Native Proteins and Derivatives
Innovative Research Inc Hmn Plasmin Immobilized 1ml
Human Plasmin Immobilized 1ml - Human Plasmin Immobilized has been purified from Human Plasma using affinity chromatography then immobilized to an agarose support. This is a resin buffered in 0.1M HEPES; 0.1M NaCl; 0.02% Sodium Azide; pH 7.4 coupled and a purity of >95%. This product is useful activation of single-chain tPA and uPA to the two-chain form and conversion of plasminogen from its native Glu form to the Lys form by removing the first 77 amino acids. More Details Source Human Plasma Purification Chromatographically purified Purity >95% Storage Conditions 4 C
Cayman Chemical N-methyl MesoporphyrIn IX 5mg
A ferrochelatase inhibitor and turn-on biosensor for DNA; inhibits ferrochelatase in mouse liver mitochondria in vitro; inhibits ferrochelatase in mice at 80 nmol, i.v. leading to porphyrin accumulation in isolated liver mitochondria; has been used as a turn-on biosensor for target DNA sequences when used in complex with a G-quadruplex-forming sequence fused to a DNA sequence complementary to the target sequence; ex/em = 399/610, respectively
Cayman Chemical AFP 07free acId 500ug
A 7,7-difluoroprostacyclin derivative that acts as a selective and highly potent agonist for the IP receptor (Ki = 0.561 nM); shows weaker affinity for EP receptors, with Ki values of > 100 nM for EP1-3 and > 10 nM for EP4
HUMABIOLOGICS INC HumaDerm - Human Skin Collagen Type I, Lyophilized-25 mg. HumaDerm is ideal for 2D & 3D cell culture, organoids, hydrogels, bioinks, and many other regenerative medicine applications. >95% purity.
HumaDerm is the only affordable lyophilized native human skin collagen for hydrogel, organoids, tissue modeling, bioink, and other regenerative medicine applications. The optimal concentration may vary depending on cell type and application and must be optimized for best results. It is soluble in dilute acid at pH ~2.0. It is isolated from human skin sourced strictly from American Association of Tissue Banks (AATB) accredited and FDA registered tissue banks and organ procurement organizations (OPOs). HumaDerm is manufactured under ISO 13485 certified and GMP-compliant quality systems. HumaDerm is obtained from human tissue that has been tested negative for a minimum of HIV-1 and -2, hepatitis B, and hepatitis C as well as other infectious agents. HumaDerm is for research use only and is not intended for human use, diagnosis, screening, household, food, or other uses. Lyophilized HumaDerm should be stored at -20 °C upon receipt.
Biotium MAP3K1 (Mitogen-Activated Protein Kinase Kinase Kinase 1)(2F6), CF647 conjugate, 0.1mg/mL
Mitogen-activated protein (MAP) kinase cascades are activated by various extracellular stimuli, including growth factors. The MEK kinases (also designated MAP kinase kinase kinases, MKKKs, MAP3Ks or MEKKs) phosphorylate and thereby activate the MEKs (also called MAP kinase kinases or MKKs), including ERK, JNK and p38. These activated MEKs in turn phosphorylate and activate the MAP kinases. The MEK kinases include Raf-1, Raf-B, Mos, MEK kinase-1, MEK kinase-2, MEK kinase-3, MEK kinase-4 and ASK 1 (MEK kinase- 5). MEK kinase-1 activates the ERK and c-Jun NH2-terminal kinase (JNK) pathways by phosphorylation of MAP2K1 and MAP2K4, and also activates the central protein kinases of the NFB pathway, CHUK and IKBKB. Additionally, MEK kinase-1 uses an E3 ligase through its PHD domain, a RING-finger-like structure, to target proteins for degradation through ubiquitination.